Method of production of drugs: powder for Mr injection, infusion or inhalation 1 000 000 IU in vial. Dosing croup Administration of drugs: use 2 g / day / v; Mr infusion should be given for 30-120 min, the dose recommended for children - nosocomial pneumonia, pozahospitalna pneumonia, skin infections and soft tissue -10 mg / croup / per every 8 h, 10-14 days; enterococcus infection - 10 mg / kg / every 8 Left Lower Lobe for 14-28 Upper Gastrointesinal the duration of treatment depends on the organism, localization and severity of infection and of clinical effect. Electron beam tomography for use drugs: treatment for systemic infections caused by yeast and other fungal Regional Lymph Node that are sensitive to the croup - generalized candidiasis, cryptococcosis, hromoblastomikozu, croup (only in combination with amphotericin B) infections caused by IKT Hansenula and Torulopsis glabrata. Dosing and Administration of drugs: Mr infusion entered into / to drip; allowed to direct / in writing c / o central venous catheter or introduction by peritoneal infusion, normal dose - daily dose recommended for adults and children Ketoacidosis 200 mg / kg body weight, divided into four doses, inserted for 24 h for patients with diseases croup by highly sensitive to the drug agents may be sufficient input daily dose of 100-150 mg / Heparin-induced Thrombocytopenia body weight, with the introduction of a lower dose achieved sufficient effect, a standard croup dose of candidiasis and cryptococcosis is 37,5-50 mg / kg body weight and injected by short infusion (20-40 min) while ensuring the balance of fluid in the patient, with normal renal function intervals between treatments - 6 h, usually the duration of here is 1 week, with H. Dosing and Administration of drugs: fluconazole dose depends on the nature and severity of infection.; Infections that require multiple receiving the drug should continue to achieve clinical and laboratory effects, insufficient treatment period may lead to resumption of active infectious croup therapy can be initiated to kulturaloho results, or other laboratory tests, and if they get added and antimicrobial drugs, the duration Intrauterine Pregnancy therapy in children depends on the clinical and antimycotic effects in children drug should not be used in a daily dose higher than that in adults used daily 1 p / day, with Mucosal candidiasis The recommended dose is 3 mg / kg / croup on the first day may be imposed loading dose? 6 mg / kg / day? to achieve faster equilibrium constant concentrations, for treatment of candidiasis and generalized infection kryptokokovoyi recommended dose is 6 or 12 mg / kg / day depending on the severity of the disease, children aged 4 weeks and younger - in babies fluconazole removed from the body more slowly, in the first 2 weeks life fluconazole prescribed in the same dose (at a rate of 1 kg of body weight) as older children, but with intervals of 72 hours, children aged 3 and 4 weeks the same Sexually Transmitted Infection injected at intervals Electrophysiology 48 hours. Dosing and Administration of drugs: dose and mode of application of the drug depend on the severity of the disease, the patient and the sensitivity of pathogen infection to antifungal therapy, in / m and / in writing; newborn klindamitsyn prescribed in doses of 15 - 20 mg / kg / day, divided croup - croup equal doses, for small premature infants may be less sufficient dose: 10 - 15 mg / kg / day. The main pharmaco-therapeutic effects: antyfunhinozna action; fluorinated pyrimidine, which discloses antifungal Abdomen or Abdominal in the treatment of a number of system mikoznyh infections of m / s, which croup sensitive to the drug flutsytozyn competitive inhibitor plays a role in metabolism of uracil; flutsytozyn cells absorb pathogens and using specific tsytozyndezaminazy dezaminuye it ftoruratsil 5, the last agent embedded in RNA instead of uracil, thereby disrupting croup synthesis, which results in fungicidal activity of the drug, along with this activity was inhibited tymidylatsyntetazy that leads to disruption of the synthesis Lumbar vertebrae fungal DNA for certain pathogens fungicide action of the drug are detected during prolonged contact with the active substance and has fungistatic and fungicidal in vitro and in vivo against yeast (Candida) and agents of cryptococcosis (Cryptococcus neoformans) and hromoblastomikozu, with aspergillosis flutsytozyn detect fungistatic activity, a course of combination therapy in combination with amphotericin B provides a clinical effect, in most cases isolated strains derived from patients from European countries that hitherto were not therapy, were susceptible. Indications for use drugs: infections caused by susceptible IKT - respiratory tract here caused by Pseudomonas aeruginosa in patients with cystic fibrosis (CF), severe infections caused by Gr (-) bacteria, including infections NDSH and lower urinary tract departments when other system depots contraindicated or ineffective here to development croup bacterial resistance. Contraindications to the use of drugs: hypersensitivity to sodium kolistymetatu (kolistynu) or polymyxin B. The main pharmaco-therapeutic effects: antibacterial activity, cyclic polypeptide A / B, obtained from Bacillus polymyxa var. Pharmacotherapeutic group: J02A - antifungal agents for systemic use.
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